• It is well established that work can influence health

  2018-11-05

  

  It is well-established that work can influence health and wellbeing in both positive and negative ways (Ross & Mirowsky, 1995; LaMontagne & Keegel, 2009; van der Noordt, IJzelenberg, Droomers, & Proper, 2014). There also evidence that persons with disability have poorer health and wellbeing compared

• br Statistical analyses We estimate

  2018-11-05

  

  Statistical analyses We estimate one model for each health outcome. For the physical markers of health, as well as self-rated health we estimate model 1, while for the health behaviour outcomes we estimate model 2:where Y is the outcome variable; MAB is the maternal age at the time of birth for t

• br Distinguishing features of and selected

  2018-11-05

  

  Distinguishing features of, and selected tensions within, a model-based perspective A model-based perspective emphasizes the processes producing outcome variation, and observed data are used to characterize that data-generating process. This is the majority perspective in statistical textbooks, i

• The study adds to the literature

  2018-11-05

  

  The study adds to the literature on place of death by focusing on a sub-Saharan African country, Zambia, where adult mortality is high and has been largely attributed to HIV/AIDS. Zambia\'s National Health Policy recognizes the large unmet need of and necessity to upscale palliative care services fo

• International comparisons are also valuable for studies eval

  2018-11-05

  

  International comparisons are also valuable for studies evaluating the population-level number of deaths attributable to a behavioral risk factor because these studies often rely on estimates of death risks from the behavioral factor under investigation (Preston & Stokes, 2011; Rostron, 2011). In su

• Research quantifying community capacity has identified stati

  2018-11-05

  

  Research quantifying dgat inhibitor capacity has identified statistically significant differences amongst neighbourhoods (Jung & Rhee, 2013) and between towns (Lovell et al., 2015a), thus confirming the importance of place to our social relationships. Place is recognised by geographers as those aspe

• br Conflicts of Interest br Author Contributions br

  2018-11-05

  

  Conflicts of Interest Author Contributions Acknowledgments This work was supported by a Grant-in-Aid for Scientific Research (KAKENHI) from the Japan Society for the Promotion of Science (JSPS) and the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) (Grant num

• ppar pathway Quantitative sensory testing QST is a

  2018-11-05

  

  Quantitative sensory testing (QST) is a standardized technique to assess human somatosensory function and document altered nociceptive signal processing (Backonja et al., 2013). By determining pain and detection threshold to external mechanical and thermal stimuli, sensory profiles are generated tha

• br Methods br Results br

  2018-11-05

  

  Methods Results Discussion Peritoneal micro-metastases are a common occurrence and portend poor prognosis for many malignancies including ovarian, gastric, and pancreatic cancer (Ferrone et al., 2006; Merchant et al., 1999; Bentrem et al., 2005; Burke et al., 1998; Yachida et al., 2002; Yos

• br Author Contributions br Disclosures

  2018-11-05

  

  Author Contributions Disclosures Acknowledgments Introduction Prostate cancer (PCa) is the second most common cause of male cancer death in the United States, and there is an urgent need to identify the key mechanisms that drive clinical disease progression and its response to treatment,

• br Relationship of Fatty Liver

  2018-11-05

  

  Relationship of Fatty Liver with the Metabolic Syndrome Traditionally deemed to be the “hepatic manifestation of the metabolic syndrome”, NAFLD is more correctly deemed to be bi-directionally linked with either the Metabolic Syndrome (MetS) or its individual components. Indeed, on the one hand me

• Finally we found that macroscopic analysis of

  2018-11-05

  

  Finally, we found that macroscopic analysis of whole tumours could predict response, and baseline Ktrans was the strongest predictor, which suggests VEGF is main determinant of vascular leakiness, though not necessarily angiogenesis. Although baseline gene expression did not strongly correlate with

• br Methods Approximately mL of

  2018-11-05

  

  Methods Approximately 7.5mL of whole blood was obtained by venipuncture into citrate-coated tubes under vacuum. All whole blood samples were processed within 12h after the blood draw. Processing started by centrifuging the whole blood at 500g, and after removal of the buffy layer by aspiration, t

• In this issue of Matsumoto

  2018-11-05

  

  In this issue of , Matsumoto et al. report the second clinical trial of nationally-regulated encapsulated porcine islet xenotransplantation, conducted in Argentina (). From their previous experience, the authors speculated that a large islet mass was susceptible to injury from oxygen and/or nutrient

• The extreme genetic diversity between HIV subtypes has

  2018-11-05

  

  The extreme genetic fccp between HIV-1 subtypes has phenotypic consequences in vitro including differential HIV-1 mRNA transcriptional control (Montano et al., 2000; van et al., 2004), protease activity (Velazquez-Campoy et al., 2001), integration site selection (Demeulemeester et al., 2014), MHC c

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