• The mechanism of enhanced anti

  2018-11-01

  

  The mechanism of enhanced anti-tumor activity of the FASN and taxane drug combination in our studies includes sensitization of tumor Senexin B to FASN inhibition-mediated gene expression changes and inhibition of beta-catenin signaling but not Akt signaling. It remains possible that sensitization t

• How does MA exert an effect on

  2018-11-01

  

  How does MA-5 exert an effect on various mitochondrial diseases even when the ETC system is disturbed? ATP production is typically described based on the chemiosmotic theory that the movement of protons across an electrochemical potential difference provides the energy needed to produce ATP (Mitchel

• Objective En resumen el saving glut aduce que una

  2018-11-01

  

  En resumen, el saving glut aduce que una reconfiguración de los flujos de capital promovió un exceso de oferta de fondos prestables, el cual se sumó Objective una nueva estrategia de inversión en los mercados financieros, que comprimió los premios de los bonos y terminó por deprimir la tasa de inter

• br Data The data in

  2018-11-01

  

  Data The data in this data article has been gathered under a ‘Direct geothermal purchase apexbio dilution research and demonstration project’ run under the Sustainable Energy Pilot Demonstration (SEPD) program funded by the state government of Victoria, Australia. Under this project, around 20 b

• The diagnosis of pre eclampsia requires

  2018-11-01

  

  The diagnosis of pre-eclampsia requires not only skilled health providers, but accurate medical devices that are appropriate for target settings, enabling users to identify pre-eclamptic women when the condition can be managed. In low- and middle-income countries (LMICs) access to the types of medic

• br Discussion As numerous previous studies Fransson et

  2018-11-01

  

  Discussion As numerous previous studies (Fransson et al., 2007; Gao et al., 2009b; Smyser et al., 2010; Fransson et al., 2011; Gao et al., 2011; Smyser et al., 2011; Alcauter et al., 2013; Gao et al., 2013; Alcauter et al., 2014; Gao et al., 2014a; Gao et al., 2014b; Gao et al., 2014) have delin

• We investigate two facets of emotional

  2018-11-01

  

  We investigate two facets of emotional functioning, which are grounded in the temperament and personality literature—negative emotionality and resiliency (Eisenberg et al., 2000; Eisenberg et al., 1997a; Eisenberg et al., 1997b; Eisenberg and Spinrad, 2004; Eisenberg et al., 2003). Negative emotiona

• br Methods br Results br Discussion In a transdiagnostic

  2018-11-01

  

  Methods Results Discussion In a transdiagnostic sample of anxious youth, greater laboratory-assessed vigilance to threat was associated with greater real-world use of avoidance (distraction and suppression) in the wake of negative events. Given the high clinical relevance of real-world avoi

• One explanation for the range of

  2018-11-01

  

  One explanation for the range of findings observed in the current study is that there may be a developmental delay in the formation of the cortical–cortical and corticospinal motor networks in TS. As noted above, motor threshold is thought to depend upon the recruitment of a coherent population of c

• In the current study differences in brain activity

  2018-11-01

  

  In the current study, differences in orexin agonist activity and precuneus functional connectivity were observed based on adolescents’ level of sexual risk behavior specifically, rather than their general engagement in risky behavior. This finding may be due to several unique aspects of adolescent

• In PS in vivo data showed

  2018-11-01

  

  In PS, in vivo data showed an increase of the gene expression profile of visfatin, and in vitro data showed a visfatin enhanced tumor necrosis factor-α-induced CXC chemokine ligands 8 and 10 as well as CC chemokine ligand 20 secretions and mRNA expression in human keratinocytes. Thus, visfatin may b

• Note that the so called model of

  2018-11-01

  

  Note that the so-called model of “narrow” particle-binder interfaces [7] is used in the calculation presented below. In this model, it is assumed that the width of the map3k8 boundary is much smaller than the size of movable cellular automaton. Moreover, the assumption of ideal adhesion of the comp

• Lin et al investigated the explosion

  2018-11-01

  

  Lin et al. investigated the explosion characteristics of nano-aluminum powders with particle sizes of 35, 75, and 100 nm in a 20-liter spherical explosion chamber [64]. The results have indicated that the maximum explosion pressure and the maximum rate of pressure rise mainly depend on the dust conc

• Con tal fin Ferrajoli analiza cuatro modelos

  2018-11-01

  

  Con tal fin, Ferrajoli analiza cuatro modelos de configuración posible de las diferencias: 1) indiferencia jurídica de las diferencias, 2) diferencia jurídica de las diferencias, 3) homologación jurídica de las diferencias y 4) igual valoración jurídica de las diferencias (Ferrajoli 2010). Este últi

• Sandblasting was identified as a key

  2018-10-31

  

  Sandblasting was identified as a key-factor in establishing a durable bond between the luting agent and the ceramic, when combined with 10-Methacryloyloxyde-cyl dihydrogen phosphate (MDP monomer), either contained in the adhesive primer (as in the present study) or in the cement itself [59,68,69]. O

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