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br Materials and Methods br Results br Discussion In
2018-10-30
Materials and Methods Results Discussion In this study, we identified several key developmental and stem cell regulatory genes as potential biomarkers of arsenic exposure in the fetal placenta. Our results also revealed extensive sexual dimorphism in the associations between placental gene
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br Declaration of Interests br Acknowledgments This study
2018-10-30
Declaration of Interests Acknowledgments This study was funded by the French Centre National de la Recherche Scientifique, the Université Grenoble Alpes, and the Direction de la Recherche Clinique et de l\'Innovation (DRCI) Centre Hospitalier Universitaire de Grenoble. LS thanks to Damascus Un
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Using an additive model integrated in
2018-10-30
Using an additive model integrated in the CaTS, we had 80% power for the overall dataset (961 cases and 3260 controls), assuming a minor disease allele frequency of 0.20, a genotypic relative risk for this variant of 1.31, a prevalence of neuropathic pain in the diabetic population of 0.25, and the
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br Methods br Results br Discussion Prospective testing of
2018-10-30
Methods Results Discussion Prospective testing of clinical risk models is imperative for assessing validity. We tested the performance of tPERSEVERE prospectively and found that it oxycodone hydrochloride cost performed poorly. One possible reason for failure is that the originally derived
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br Hedgehog Pathway Inhibition Hedgehog Hh is a highly
2018-10-30
Hedgehog Pathway Inhibition Hedgehog (Hh) is a highly conserved signaling pathway, components of which include cell surface receptor Patched-1 (PTCH1), transmembrane receptor Smoothened (SMO), and three glioma associated family transcription factors (GLI) (Khan et al., 2015). It is involved with
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One of our most intriguing
2018-10-30
One of our most intriguing findings in the present study is that decreased goblet cell differentiation and mucus production were associated with severe inflammation in response to DSS in Adam17Mx1-Cre+ mice. Complete knockout of the Adam17 gene displays multiple pathological changes in several organ
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The recent Zika virus ZIKV outbreak has been
2018-10-30
The recent Zika virus (ZIKV) outbreak has been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization in February 2016. It started in Brazil in 2015, rapidly spread through South and Central America, and is expected to reach the continental US in the sum
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br Materials and Methods br Results br Discussion Previous
2018-10-30
Materials and Methods Results Discussion Previous studies have indicated that irisin could improve dyslipidemia and hepatic steatosis in mice (Xiong et al., 2015). The decrement of lipid accumulation in hepatocytes was proposed to result mainly from the suppression of triglyceride synthesis
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Notably the arrival reticulocyte count contributed strongly
2018-10-30
Notably, the arrival reticulocyte count contributed strongly to the predictive score, being significantly higher on day 1 than at steady state for 2°ACSs (272±88 vs 237±95, respectively p=0.006, n=33 paired values), while the VOC group\'s values were stable (p=0.98). Moreover, increased reticulocyte
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Zinc is an essential nutrient for microbial growth
2018-10-29
Zinc is an essential nutrient for microbial growth, but can be toxic in excess (Blencowe and Morby, 2003; Coleman, 1998). The delicate balance between zinc sufficiency and toxicity is maintained by bacterial metal homeostasis systems (Klaus, 2005; Moore and Helmann, 2005). The GAS metalloregulator,
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The shape of the observed PK concentration
2018-10-29
The shape of the observed PK concentration-time profile following IH administration was consistent with the IM PK profile (Fig. 3). Plasma oxytocin was detectable in all subjects at the first sampling time (3min post-dose) and remained quantifiable in 5/16 subjects up to 4h following IM administrati
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Ahora bien tal y como se muestra
2018-10-29
Ahora bien, tal y como se muestra en la Imagen 1, el sistema tributario mexicano que funcionó desde 1917 hasta 1935 se conformaba de once grandes rubros fiscales cobrados y administrados por la shcp. En términos generales, cuando un contribuyente no atendía al pago de las contribuciones se le determ
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br Data The physical data for input parameters of
2018-10-29
Data The physical data for input parameters of different materials used for designing a highly efficient CIGS solar cell have been presented in Table 1. Along with this dataset, the contact parameters and the conditions under which the simulation was conducted have been demonstrated in Tables 2 a
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br Acknowledgements Many thanks to C Johnson for
2018-10-29
Acknowledgements Many thanks to C. Johnson for providing unpublished data. This research was supported by an Australian Postgraduate Award and Australian Government Caring for our Country 2 Target Area Grant 2013/14 (Project ID: TAG14-00542) Bettongia tropica population status, viability and impa
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Technological innovation is an essential driver of
2018-10-29
Technological innovation is an essential driver of human and economic development. It can improve the functioning of markets (), promote government accountability (), build human capital (), and reduce the risks we face from global environmental change (). Yet designing technologies that improve the
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